CDx unit has strong expertise covering the whole spectrum of genetic biomarker development and analysis from clinical sample storage and management, DNA/RNA isolation from various types of samples to qPCR, ddPCR, Sanger sequencing and NGS based genetic assay development and validation. Additionally, through our internal and external partnerships, we can reach other expertise like bioinformatics, protein based biomarker assay development and companion diagnostics development.
Nucleic Acid Isolation (DNA, RNA, and miRNA)
Tissues, including frozen tissues and FFPE samples
Mutation analysis (EGFR, KRAS, BRAF,PI3K, BRC-ABL, T315I, ALK, NRAS,UGT1A1, MGMT et.al);
Gene fusion analysis (ALK, ROS1 et.al.);
NGS: BRCA1/BRCA2, cancer hotspot panels